The Bundesliga side may need to sell the Belgian if they do not qualify for the Champions League, with Manchester United and former-club Chelsea looking in.
De Bruyne has been in superb form this season, scoring 11 goals and providing 14 assists, attracting the attention of a number of European clubs.
The 23 year-old joined the side from Chelsea in January of last year for £18m and has so far lived up to the billing.
Manchester United have been linked with the Belgian international, whilst Atletico Madrid are also thought to be keen to bring him in.
Wolfsburg sporting director Klaus Allofs has admitted the club can only hold onto their star if they can maintain their second place position in the table, with Manchester United looking likely to secure Champions League football next season.
“It is possible that we would have to part with him [De Bruyne] if we didn’t have Champions League football, but anyone who does want him would have to dig deep into their pockets to satisfy our demands,” Allofs told Kicker.
By Phil Wellbrook