Italy boss and yet to be named as the next Chelsea manager Antonio Conte, has set his sights on the two Roma players as part of his major rebuilding plans.
Belgium midfielder Nainggolan, 27, is also being heavily targeted by Liverpool, However, Chelsea believe they will get beat The Reds to the deal.
Chelsea also face competition from Everton , as they are set to conjure up an offer for Greek centre back Manolas, 24, but the Blues aren’t worried too much about competition from the Mersyside outfit.
Chelsea are set to make a move for more defensive reinforcements with Captain John Terry yet to be offered a new deal by the club.