The team news from the Etihad Stadium has been announced, and here are the two starting line-ups.
Manchester City: Pantilimon, Zabaleta, Kompany (c), Demichelis, Clichy, Fernandinho, Yaya Toure, Nasri, Silva, Aguero, Negredo.
Manchester City subs: Hart, Lescott, Kolarov, Garcia, Navas, Milner, Dzeko
Arsenal: Szczesny, Sagna, Mertesacker, Koscielny, Monreal, Flamini, Wilshere, Ramsey, Ozil, Walcott, Giroud
Arsenal subs: Fabianski, Vermaelen, Arteta, Rosicky, Cazorla, Gnabry, Bendtner
Who will come out on top?