The Uruguayan international is set to sign for the Premier league new boys in a deal reportedly around £11.8 million.
The versatile winger was seemingly destined for merseyside but talks carried on for so many weeks, that Bologna got tired of waiting for a concrete offer.
Southampton could be looking at one of the best deals the club has ever done, with Ramirez a reported target for many of the top clubs in Europe.
The transfer has not yet gone through, but the south coast team look to be favourites to get the signature of the highly-rated player.
TomDunn