Home Football Top 10 most prolific strikers in the Premier League FootballPremier LeagueArsenalChelseaEvertonLiverpoolManchester CityManchester UnitedEnglandSouthamptonTottenham Top 10 most prolific strikers in the Premier League By Liam Chambers - Dec 19, 2016 5 0 FacebookTwitterPinterestWhatsApp 4) Alexis Sanchez (Arsenal) 12 goals; 1347 minutes played; 112 minutes per goal